Vimentin Recombinant Antibody

Vimentin Recombinant Antibody

• Description: Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
• CAS Number: 9000-83-3
• UniProt: P08670
• Host: Mouse
• Immunogen: A portion of amino acids 2-466 from the human protein was used as the immunogen for the recombinant VIM antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Type: Recombinant
• Applications: WB, IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Aliquot the recombinant VIM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This recombinant VIM antibody is available for research use only.