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SOX9 Antibody

CAT: 0800-V8969SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8969SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P48436
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length SOX9 protein was used as the immunogen for the SOX9 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
PCRP-SOX9-1A2
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the SOX9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX9 antibody is available for research use only.
Storage Conditions
Aliquot the SOX9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the SOX9 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using SOX9 antibody (clone PCRP-SOX9-1A2) . These results demonstrate the foremost specificity of the PCRP-SOX9-1A2 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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