Galectin 3 Antibody

• Description:

  Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

• Specifications:

  Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

• UniProt:

  P17931

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 150-200 from the human protein was used as the immunogen for the Galectin 3 antibody.

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG κ

• Clone:

  LGALS3/7036R

• Type:

  Recombinant

• Applications:

  IHC-P, WB

• Purity:

  Protein A/G affinity

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the Galectin 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Galectin 3 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Galectin 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the Galectin 3 antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Location:

  Cytoplasmic, nuclear

• Image Legend:

  IHC staining of FFPE human colon tissue with Galectin 3 antibody (clone LGALS3/7036R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.