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Recombinant Interferon gamma Antibody

CAT: 0800-V8308SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8308SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-g and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-g. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-a/b (type I interferon) .
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P01579
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFNG was used as the immunogen for the recombinant Interferon gamma antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
IFNG/3996R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the recombinant Interferon gamma antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant Interferon gamma antibody is available for research use only.
Storage Conditions
Store the recombinant Interferon gamma antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant Interferon gamma antibody should be determined by the researcher.
Location
Cytoplasmic, membranous, extracellular (secreted)
Image Legend
IHC staining of FFPE human kidney with recombinant Interferon gamma antibody (clone IFNG/3996R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

UniProtKB · P01579

Interferon gamma

IFNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma
EC number
—
Processing
Precursor
Secondary accessions
B5BU88, Q53ZV4
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Antiviral defenseGrowth regulation

PTM

Cleavage on pair of basic residuesGlycoproteinPyrrolidone carboxylic acid

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal

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