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Interferon gamma Antibody

CAT: 0800-V4305-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V4305-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFN-gamma and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-gamma. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-A/B (type I interferon) .
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
P01579
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFN-gamma was used as the immunogen for the Interferon gamma antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
IFNG/464
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Interferon gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Interferon gamma antibody is available for research use only.
Storage Conditions
Aliquot the Interferon gamma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Interferon gamma antibody should be determined by the researcher.
Location
Cytoplasm, Extracellular (secreted)
Image Legend
SDS-PAGE analysis of purified, BSA-free Interferon gamma antibody (clone G-23) as confirmation of integrity and purity.

UniProtKB · P01579

Interferon gamma

IFNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma
EC number
—
Processing
Precursor
Secondary accessions
B5BU88, Q53ZV4
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Antiviral defenseGrowth regulation

PTM

Cleavage on pair of basic residuesGlycoproteinPyrrolidone carboxylic acid

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal
Product Datasheet
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