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Interferon gamma Antibody

CAT: 0800-R30566Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30566Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interferon gamma is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFNg, which is under genetic control, can influence the development of fibrosis in lung allografts. It is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFNg and expression might be important for the development of tuberculosis. It activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, Interferon gamma has important immunoregulatory functions and plays an important role in the control of neointima proliferation.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P01579
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human IFNg (KRKRSQMLFRGRRASQ) was used as the immunogen for this Interferon gamma antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Interferon gamma antibody is available for research use only.
Storage Conditions
After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Interferon gamma antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, membranous, extracellular (secreted)
Image Legend
Western blot testing of Interferon gamma antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3. 2.5ng; 4: 1.25ng
Product Datasheet
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