Products for Research Use Only
RegisterLogin

Cyclin B2 Antibody / CCNB2

CAT: 0800-V8196SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V8196SAF-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1) . The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating)
UniProt
O95067
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full-length Xenopus laevis Cyclin B2 protein was used as the immunogen for this Cyclin B2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
X29.2
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the Cyclin B2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Cyclin B2 antibody is available for research use only.
Storage Conditions
Store the Cyclin B2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Cyclin B2 antibody should be determined by the researcher.
Image Legend
SDS-PAGE analysis of purified, BSA-free Cyclin B2 antibody (clone X29.2) as confirmation of integrity and purity.

UniProtKB · O95067

G2/mitotic-specific cyclin-B2

CCNB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCNB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KM93, Q6FI99
Protein keywords

Biological process

Cell cycleCell divisionMitosis

Molecular function

Cyclin

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Related Products

CatalogName
RQ5963CCNB1 Antibody / Cyclin B1
RQ4829CCNE2 Antibody / Cyclin E2
V3780-100UGCyclin A2 Antibody / CCNA2
F52197-0.08MLCyclin D2 Antibody (CCND2)
F52188-0.08MLCyclin B Antibody (CCNB1)
F52191-0.4MLCyclin B1 Antibody (CCNB1)
F50281-0.4MLCyclin A2 Antibody (CCNA2)
F52196-0.08MLCyclin D2 Antibody (CCND2)
F41189-0.4MLCyclin B1 Antibody (CCNB1)
F41189-0.08MLCyclin B1 Antibody (CCNB1)

Alternative Products

CatalogName
abx034755-01Cyclin B2 (CCNB2) Antibody
GTR18575044Cyclin B2 Antibody / CCNB2
abx335758-01Cyclin B2 (CCNB2) Antibody (FITC)
TRV-020657-01Monoclonal Antibody to Cyclin B2 (CCNB2)
A02040-2Anti-Cyclin B2 CCNB2 Antibody
MBS2028332-01Polyclonal Antibody to Cyclin B2 (CCNB2)
CAU23449-01Cyclin B2 (CCNB2) Polyclonal Antibody
MBS1753014-01Anti-Cyclin B2/CCNB2 Antibody
abx335757-01Cyclin B2 (CCNB2) Antibody (HRP)
abx335759-01Cyclin B2 (CCNB2) Antibody (Biotin)

Popular Products