CCNE2 Antibody / Cyclin E2

CAT: 0800-RQ4829Size: 100 µLDry Ice: NoHazardous: No
CAT#:0800-RQ4829Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
'G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O96020
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the CCNE2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
EDB-3
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the CCNE2 antibody at -20oC.
Limitations
This CCNE2 antibody is available for research use only.
Storage Conditions
Store the CCNE2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CCNE2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with CCNE2 antibody. Expected molecular weight: 45-50 kDa.