ROR2 Antibody

CAT: 0800-V7987-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V7987-100UGSize:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1, or the autosomal recessive skeletal disorder, Robinow syndrome.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q01974
Host
Mouse
Reactivity
Human
Immunogen
Cultured human keratinocytes were used as the immunogen for this ROR2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ROR2/1912
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the ROR2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This ROR2 antibody is available for research use only.
Storage Conditions
Store the ROR2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the ROR2 antibody should be determined by the researcher.
Location
Cell membrane, cytoplasm
Image Legend
IHC staining of FFPE human kidney with ROR2 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Related Products

CatalogName
V4739-20UGROR gamma Antibody / RORC
RQ6921ROR beta Antibody / RORB
RQ7200ROR gamma Antibody / RORC
V7575IHC-7MLRORC Antibody / ROR gamma
F54563-0.08MLROR alpha Antibody / RORA
V7575-100UGRORC Antibody / ROR gamma
V4739SAF-100UGROR gamma Antibody / RORC
V7575SAF-100UGRORC Antibody / ROR gamma
F54563-0.4MLROR alpha Antibody / RORA
V7575-20UGRORC Antibody / ROR gamma

Alternative Products

CatalogName
MBS8582382-01ROR2 Antibody

Popular Products