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ROR gamma Antibody / RORC

CAT: 0800-RQ7200Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7200Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P51449
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids Q286-E511) was used as the immunogen for the ROR gamma antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ROR gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ROR gamma antibody is available for research use only.
Storage Conditions
After reconstitution, the ROR gamma antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ROR gamma antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human HeLa cells with ROR gamma antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= ROR gamma antibody.

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