ROR alpha Antibody / RORA

CAT: 0800-F54563-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F54563-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P35398
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 193-222 from the human protein was used as the immunogen for the ROR alpha antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ROR alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ROR alpha antibody is available for research use only.
Storage Conditions
Aliquot the ROR alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the ROR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear
Image Legend
Western blot testing of human brain lysate with ROR alpha antibody. Predicted molecular weight ~59 kDa.

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