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Prolactin Antibody / PRL

CAT: 0800-V7620IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V7620IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prolactin is a growth factor that is secreted by the anterior pituitary. It is necessary for the proliferation and differentiation of the mammary glands. Prolactin is useful in the classification of pituitary tumors and study of pituitary disease. It also plays a role in the development of mammary cancer, functioning dually as a mitogen and a differentiating agent.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P01236
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein corresponding to amino acids 63-201 was used as the immunogen for the Prolactin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PRL/2641
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the Prolactin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Prolactin antibody is available for research use only.
Storage Conditions
Store the Prolactin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Applications Notes
Optimal dilution of the Prolactin antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human pituitary tissue with Prolactin antibody (clone PRL/2641) . Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P01236

Prolactin

PRL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01236
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PRL
EC number
—
Processing
Precursor
Secondary accessions
Q15199, Q92996
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

Hormone

Biological process

Lactation

Cellular component

Secreted

Domain

Signal

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