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PRL Antibody / Prolactin

CAT: 0800-V7606-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V7606-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The PRL gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. [RefSeq]
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P01236
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein corresponding to amino acids 63-201 was used as the immunogen for the PRL antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PLCN-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the PRL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This PRL antibody is available for research use only.
Storage Conditions
Store the PRL antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the PRL antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Image Legend
IHC testing of FFPE human pituitary tissue with PRL antibody (clone PLCN-1) . Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P01236

Prolactin

PRL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01236
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PRL
EC number
—
Processing
Precursor
Secondary accessions
Q15199, Q92996
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

Hormone

Biological process

Lactation

Cellular component

Secreted

Domain

Signal

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