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Prolactin Antibody / PRL

CAT: 0800-RQ8144Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8144Size:100 µg
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Description
Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, prolactin already existed in the oldest known vertebrates (fishes) where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P01236
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids A36-D206) was used as the immunogen for the Prolactin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Prolactin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Prolactin antibody is available for research use only.
Storage Conditions
After reconstitution, the Prolactin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Prolactin antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with Prolactin antibody. Predicted molecular weight ~26 kDa.

UniProtKB · P01236

Prolactin

PRL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01236
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PRL
EC number
—
Processing
Precursor
Secondary accessions
Q15199, Q92996
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

Hormone

Biological process

Lactation

Cellular component

Secreted

Domain

Signal

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