Products for Research Use Only
RegisterLogin

Recombinant CELA3B Antibody / Elastase 3B

CAT: 0800-V7454-20UGSize: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V7454-20UGSize:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [RefSeq]
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P08861
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 82-238 from the human protein were used as the immunogen for the recombinant CELA3B antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
ELTS3B-4R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the recombinant CELA3B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant CELA3B antibody is available for research use only.
Storage Conditions
Store the recombinant CELA3B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
IHC testing of human pancreas with recombinant CELA3B antibody (clone ELTS3B-4R) . Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.

UniProtKB · P08861

Chymotrypsin-like elastase family member 3B

CEL3B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08861
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CELA3B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.70
Processing
Precursor
Secondary accessions
B2RE44, P11423, Q5VU28, Q5VU29, Q5VU30
Protein keywords

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinZymogen

Molecular function

HydrolaseProteaseSerine protease

Domain

Signal
Product Datasheet
Loading...

Related Products

CatalogName
V3436-100UGElastase 3B Antibody / CELA3B
V8906-20UGCELA3B Antibody / Elastase 3B
V3449-20UGCELA3B Antibody / Elastase 3B
V8906-100UGCELA3B Antibody / Elastase 3B
V3449SAF-100UGCELA3B Antibody / Elastase 3B
V3449-100UGCELA3B Antibody / Elastase 3B
V8906SAF-100UGCELA3B Antibody / Elastase 3B
V3436-20UGElastase 3B Antibody / CELA3B
V3436SAF-100UGElastase 3B Antibody / CELA3B
V8919-20UGChymotrypsin-like elastase family member 3B Antibody / CELA3B / Elastase 3B

Alternative Products

CatalogName
OPEF01698-1MGRecombinant Elastase CELA3B Antigen
GTR18575157Recombinant CELA3B Antibody / Elastase 3B
GTR18081812-01CELA3B Antibody / Elastase 3B
GTR18081800-01Elastase 3B Antibody / CELA3B
ANT-12028-100ugElastase-3B / CELA3B Polyclonal Antibody
TA374625Elastase (CELA3B) Rabbit Polyclonal Antibody
E55A00506Elastase-3B/CELA3B Polyclonal Antibody
TP762562Elastase (CELA3B) (NM_007352) Human Recombinant Protein
PPT-12490Human Elastase-3B/CELA3B Recombinant Protein
NBP2-53285-100ugMouse Monoclonal Elastase Antibody (CELA3B/1374)

Popular Products