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Recombinant MVP Antibody

CAT: 0800-V7386IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V7386IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases. [UniProt]
CAS Number
9000-83-3
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
Q14764
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the recombinant MVP antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
MJVP-1R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the recombinant MVP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This recombinant MVP antibody is available for research use only.
Storage Conditions
Store the recombinant MVP antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, nuclear
Image Legend
IHC staining of FFPE human breast carcinoma with recombinant MVP antibody (clone MJVP-1R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

UniProtKB · Q14764

Major vault protein

MVP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14764
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MVP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MVP
EC number
—
Processing
—
Secondary accessions
Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

CytoplasmNuclear pore complexNucleus

Biological process

mRNA transportProtein transportTranslocationTransport

Domain

Repeat

Molecular function

Ribonucleoprotein

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