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MVP Antibody

CAT: 0800-RQ5611Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5611Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
Q14764
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant protein (amino acids A2-H259) was used as the immunogen for the MVP antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
8B12
Applications
WB, IHC-P, FACS
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the MVP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MVP antibody is available for research use only.
Storage Conditions
After reconstitution, the MVP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MVP antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human lung cancer with MVP antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.

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