Ku70 + Ku80 Antibody

CAT:

800-V7202PE-100T

Size:

100 Tests

Price:

Ask

For price, please contact [email protected]

Description: Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]
CAS Number: 9007-83-4
Host: Mouse
Immunogen: A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
Clonality: Monoclonal
Isotype: IgG1 κ
Applications: FACS
Format: PE Conjugate
Buffer: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution: Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Limitations: This Ku70 + Ku80 antibody is available for research use only.

Cat	Name
GWB-D759CE	Ku70 + Ku80 Antibody
HY-P73846-04	Ku70-Ku80 Heterodimer, Human (sf9, His)
HY-P73846-02	Ku70-Ku80 Heterodimer, Human (sf9, His)
HY-P73846-01	Ku70-Ku80 Heterodimer, Human (sf9, His)
HY-P73846-03	Ku70-Ku80 Heterodimer, Human (sf9, His)
MBS8123610-01	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His Tag)
E45H52444I1-50	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His Tag)
MBS8123610-02	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His Tag)
MBS8123610-03	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His Tag)
MBS242721-02	Rabbit Polyclonal (IgG) to Human Ku70+Ku80 / XRCC6+XRCC5