Products for Research Use Only
RegisterLogin

NKX2.2 Antibody

CAT: 0800-V3314-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V3314-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
O95096
Host
Rabbit
Reactivity
Human
Immunogen
A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This NKX2.2 antibody is available for research use only.
Storage Conditions
Store the NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Titering of the NKX2.2 antibody may be required for optimal performance.
Location
Nuclear
Image Legend
IHC testing of FFPE Ewings sarcoma with NKX2.2 antibody. HIER: steam sections in 10mM citrate buffer, pH 6.0, for 10-20 min.

UniProtKB · O95096

Homeobox protein Nkx-2.2

NKX22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95096
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NKX2-2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Molecular function

ActivatorDevelopmental proteinDNA-binding

Domain

Homeobox

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

Related Products

CatalogName
RZ1250Zebrafish Nkx2.2a Antibody / Nkx2.2
F53210-0.05MLNkx2.5 Antibody
V7802SAF-100UGNKX2.8 Antibody
F45607-0.4MLNKX2.5 Antibody
F52860-0.4MLNkx2.5 Antibody
F46308-0.08MLNKX2.6 Antibody
F53210-0.2MLNkx2.5 Antibody
V7802-20UGNKX2.8 Antibody
F43599-0.08MLNKX2.4 Antibody
F53080-0.08MLNkx2.5 Antibody

Alternative Products

CatalogName
TA330256Nkx2.2 (NKX2-2) Rabbit Polyclonal Antibody
TA424071Nkx2.2 (NKX2-2) Rabbit Monoclonal Antibody
GTR18613562NKX2-2/NKX2 Rabbit Polyclonal Antibody
GTR17695319NKX2.2/NKX2 Rabbit Monoclonal Antibody
GWB-MM694ANKX2-2 Antibody
MBS9435334-01NKX2.2 Antibody
TS410419P5Nkx2.2 (NKX2-2) CytoSection

Popular Products