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Nkx2.5 Antibody

CAT: 0800-F52860-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F52860-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P42582
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
This mouse Nkx2.5 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 192-225 amino acids from the Central region of mouse Nkx2.5.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Nkx2.5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Nkx2.5 antibody is available for research use only.
Storage Conditions
Aliquot the Nkx2.5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Nkx2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of lysate from mouse stomach, rat heart tissue (left to right) using Mouse Nkx2.5 antibody at 1:1000 for each lane. Predicted molecular weight ~35 kDa, routinely observed at 35~45 kDa.

UniProtKB · P42582

Homeobox protein Nkx-2.5

NKX25_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P42582
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Nkx2-5
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P97335
Protein keywords

Technical term

3D-structureReference proteome

Molecular function

Developmental proteinDNA-binding

Domain

Homeobox

Cellular component

Nucleus

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