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VCAM1 Antibody

CAT: 0800-V2923IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V2923IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100) . It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P19320
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the VCAM1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
VCAM1/843
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the VCAM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This VCAM1 antibody is available for research use only.
Storage Conditions
Store the VCAM1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, membrane
Image Legend
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with VCAM1 antibody (VCAM1/843) .

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