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VCAM-1 Antibody

CAT: 0800-V7162-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V7162-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vascular cell adhesion molecule-1 (VCAM-1), also called L1CAM and CD106, is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [UniProt]
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT (1), Prediluted IHC only format: incubate for 30 min at RT (2)
UniProt
P19320
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the VCAM-1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CDLA106
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the VCAM-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This VCAM-1 antibody is available for research use only.
Storage Conditions
Store the VCAM-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic, membrane
Image Legend
IHC testing of FFPE human tonsil with VCAM-1 antibody (clone CDLA106) .

UniProtKB · P19320

Vascular cell adhesion protein 1

VCAM1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19320
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VCAM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
V-CAM 1, VCAM-1
EC number
—
Processing
Precursor
Secondary accessions
A8K6R7, B4DKS4, E9PDD1, Q6NUP8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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