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TGFa Antibody

CAT: 0800-V2888IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
CAT#:0800-V2888IHC-7MLSize:7 mL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P01135
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length TGF protein was used as the immunogen for the TGFa antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
TGFA/1119
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the TGFa antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This TGFa antibody is available for research use only.
Storage Conditions
Store the TGFa antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic and extracellular (secreted)
Image Legend
IHC testing of formalin-fixed, paraffin-embedded human testicular carcinoma stained with TGFa antibody (clone TGFA/1119) .

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