TGFa Antibody

• Description :

  This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

• Specifications :

  Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 min at RT

• UniProt :

  P01135

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Recombinant human full-length TGF protein was used as the immunogen for the TGFa antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  TGFA/1119

• Applications :

  IHC-P

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution :

  Store the TGFa antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This TGFa antibody is available for research use only.

• Storage Conditions :

  Store the TGFa antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• CAS Number :

  9007-83-4

• Location :

  Cytoplasmic and extracellular (secreted)

• Image Legend :

  IHC testing of formalin-fixed, paraffin-embedded human testicular carcinoma stained with TGFa antibody (clone TGFA/1119) .