Products for Research Use Only

Transferrin Receptor Antibody / CD71

CAT: 0800-V2881-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V2881-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
P02786
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the Transferrin Receptor antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
TFRC/1059
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Transferrin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Transferrin Receptor antibody is available for research use only.
Storage Conditions
Store the Transferrin Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Transferrin Receptor antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Flow cytometry testing of human Jurkat cells with Transferrin Receptor antibody (clone TFRC/1059) ; Red=isotype control, Blue= Transferrin Receptor antibody.