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Interferon alpha 2 Antibody

CAT: 0800-V2612-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V2612-20UGSize:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN- (II) . Its epitope maps between aa112-148 of IFN-II) (total aa172) . This mAb is specific for IFN- (II) and does not cross-react with IFN- (I) . The site recognized by this mAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN- (II) . Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN- (II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
CAS Number
9007-83-4
Specifications
ELISA (order the BSA-free format for coating)
UniProt
P01563
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
N39
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Interferon alpha 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Interferon alpha 2 antibody is available for research use only.
Storage Conditions
Store the Interferon alpha 2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.
Location
Cytoplasmic, extracellular (secreted)
Image Legend
SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha 2 Antibody (clone N39) . Confirmation of Integrity and Purity of the Antibody.

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