Interferon alpha Antibody

• Description:

  This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

• Specifications:

  ELISA (order the BSA-free format for coating)

• UniProt:

  P01562

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  2.52

• Applications:

  ELISA

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution:

  Store the Interferon alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This Interferon alpha antibody is available for research use only.

• Storage Conditions:

  Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes:

  Optimal dilution of the Interferon alpha antibody should be determined by the researcher.1. This clone is also referred to as clone 2-52.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic, extracellular (secreted)

• Image Legend:

  SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha Antibody (clone 2.52) . Confirmation of Integrity and Purity of the Antibody.