Interferon alpha Antibody

CAT: 0800-V2611-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V2611-20UGSize:20 µg
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Description
This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
CAS Number
9007-83-4
Specifications
ELISA (order the BSA-free format for coating)
UniProt
P01562
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
2.52
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Interferon alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Interferon alpha antibody is available for research use only.
Storage Conditions
Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Interferon alpha antibody should be determined by the researcher.1. This clone is also referred to as clone 2-52.
Location
Cytoplasmic, extracellular (secreted)
Image Legend
SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha Antibody (clone 2.52) . Confirmation of Integrity and Purity of the Antibody.

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