Interferon alpha Antibody

• Description :

  This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

• Specifications :

  ELISA (order the BSA-free format for coating)

• UniProt :

  P01562

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  2.52

• Applications :

  ELISA

• Purity :

  Protein G affinity chromatography

• Format :

  Purified

• Buffer :

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution :

  Store the Interferon alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This Interferon alpha antibody is available for research use only.

• Storage Conditions :

  Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes :

  Optimal dilution of the Interferon alpha antibody should be determined by the researcher.1. This clone is also referred to as clone 2-52.

• CAS Number :

  9007-83-4

• Location :

  Cytoplasmic, extracellular (secreted)

• Image Legend :

  SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha Antibody (clone 2.52) . Confirmation of Integrity and Purity of the Antibody.