RegisterLogin

CD45RA Antibody

CAT: 0800-V2404-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V2404-100UGSize:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CD45RA is an isoform of the human leukocyte common antigen (CD45) . Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve) .
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-2 µg/mL, Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P08575
Host
Mouse
Reactivity
Human
Immunogen
Stimulated human leukocytes were used as immunogen for this CD45RA antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PTPRC/1131
Applications
FACS, IF, WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
The CD45RA antibody (with azide) can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
Limitations
This CD45RA antibody is available for research use only.
Storage Conditions
The CD45RA antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface
Image Legend
Western blot testing of human spleen lysate with CD45RA antibody. Expected molecular weight: 147-220 kDa depending on glycosylation level.

Related Products

CatalogName
V7044-100UGCD45RO Antibody
V7031SAF-100UGCD45RB Antibody
V7031-20UGCD45RB Antibody
V2410SAF-100UGCD45RB Antibody
V2416-20UGCD45RO Antibody
V2245-100UGCD45RB Antibody
V2415-100UGCD45RB Antibody
V2415IHC-7MLCD45RB Antibody
V2242SAF-100UGCD45RB Antibody
V2242-20UGCD45RB Antibody

Alternative Products

CatalogName
abx414689-01CD45RA Antigen / PTPRC (CD45RA) Antibody
abx228505-01CD45RA Antigen (CD45RA/PTPRC) Antibody
abx134010-01CD45RA Antibody
GWB-1404ABCD45RA, Antibody

Popular Products