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CD11c Antibody

CAT: 0800-V2162-20UGSize: 20 µgDry Ice: NoHazardous: No
CAT#:0800-V2162-20UGSize:20 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL, Functional studies (order BSA/sodium azide-free format)
Host
Mouse
Reactivity
Human
Immunogen
Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HC1/1
Applications
FACS, IF, Functional studies
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CD11c antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD11c antibody is available for research use only.
Storage Conditions
Store the CD11c antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
Location
Cell surface, cytoplasmic
Image Legend
FACS staining of human PBMCs using CD11c antibody (HC1/1) .
Product Datasheet
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