CD11b Antibody / MAC-1
CAT:
800-V2161SAF-100UG
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD11b Antibody / MAC-1
- Description: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
- CAS Number: 9007-83-4
- Host: Rat
- Immunogen: B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.
- Clonality: Monoclonal
- Isotype: IgG2b κ
- Applications: FACS, IF, Functional studies
- Format: Purified
- Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
- Reconstitution: Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
- Limitations: This CD11b antibody is available for research use only.