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Dectin 1 Antibody / Clec7a

CAT: 0800-RQ6850Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6850Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene. This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q6QLQ4
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant mouse protein (amino acids Q17-L244) was used as the immunogen for the Dectin 1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Dectin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Dectin 1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Dectin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Dectin 1 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE mouse spleen tissue with Dectin 1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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