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AP2 gamma Antibody / TFAP2C

CAT: 0800-RQ6807Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6807Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor AP-2 gamma also known as AP2-gamma is a protein that in humans is encoded by the TFAP2C gene. The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q92754
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids M1-N219) was used as the immunogen for the AP2 gamma antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the AP2 gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This AP2 gamma antibody is available for research use only.
Storage Conditions
After reconstitution, the AP2 gamma antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the AP2 gamma antibody should be determined by the researcher.
Location
Nuclear
Image Legend
IHC staining of FFPE human testicular cancer tissue with AP2 gamma antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q92754

Transcription factor AP-2 gamma

AP2C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92754
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TFAP2C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AP2-gamma
EC number
—
Processing
—
Secondary accessions
B4DWK3, O00685, O00730, Q86V30, Q8IVB6, Q9P1X2
Protein keywords

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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