AP2 Antibody

• Description:

  Activator protein 2 is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P05549

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 104-133 from the human protein was used as the immunogen for this AP2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the AP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This AP2 antibody is available for research use only.

• Storage Conditions:

  Aliquot the AP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the AP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Bovine, Mouse, Rat

• CAS Number:

  9007-83-4

• Image Legend:

  AP2 antibody western blot analysis in U251 lysate. Predicted molecular weight ~47 kDa.