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Telomeric repeat-binding factor 1 Antibody / TRF1 / TERF1

CAT: 0800-RQ6806Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6806Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P54274
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids Q119-R341) was used as the immunogen for the Telomeric repeat-binding factor 1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Telomeric repeat-binding factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Telomeric repeat-binding factor 1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Telomeric repeat-binding factor 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Telomeric repeat-binding factor 1 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human A431 cells with Telomeric repeat-binding factor 1 antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

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