TRF2 Antibody (Telomeric repeat-binding factor 2)

• Description :

  Telomeric repeat-binding factor 2, also known as TERF2, TRF2, or TRBF2, is encoded in humans by the TERF2 gene. This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

• Specifications :

  Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL

• UniProt :

  Q15554

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Amino acids A81-K287 from the human protein were used as the immunogen for the TRF2 antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB, IHC-P

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2% Trehalose, 0.025% sodium azide

• Reconstitution :

  After reconstitution, the TRF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This TRF2 antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the TRF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  Optimal dilution of the TRF2 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Location :

  Nuclear

• Image Legend :

  Western blot testing of 1) rat thymus and 2) human COLO320 lysate with TRF2 antibody at 0.5ug/ml. Predicted molecular weight ~75 kDa.