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TRF2 Antibody (Telomeric repeat-binding factor 2)

CAT: 0800-R32769Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32769Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Telomeric repeat-binding factor 2, also known as TERF2, TRF2, or TRBF2, is encoded in humans by the TERF2 gene. This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
Q15554
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids A81-K287 from the human protein were used as the immunogen for the TRF2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose, 0.025% sodium azide
Reconstitution
After reconstitution, the TRF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRF2 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TRF2 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of 1) rat thymus and 2) human COLO320 lysate with TRF2 antibody at 0.5ug/ml. Predicted molecular weight ~75 kDa.

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336816Telomeric repeat binding factor 2
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405072-01Telomeric Repeat Binding Factor 1 discontinued
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