E2F3 Antibody

CAT: 800-RQ6616Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
UniProt
O00716
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids KTNNQDHNGNIPKPASKDLA from the human protein were used as the immunogen for the E2F3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the E2F3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This E2F3 antibody is available for research use only.
Storage Conditions
After reconstitution, the E2F3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the E2F3 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human 293T, 2) human SK-O-V3, 3) human K562, 4) human HEL, 5) rat brain and 6) mouse brain tissue lysate with E2F3 antibody. Predicted molecular weight: ~49 kDa but can also be observed from 56~66 kDa.