SOX7 Antibody

• Description:

  SOX7 belongs to SOX gene family and SOX proteins are transcription factors with critical roles in the regulation of diverse developmental processes. This gene is mapped to 8p23.1. SOX7 gene contains at least 2 exons. In co-transfected 293 cells, Sox7 reduced Wnt/beta-catenin-stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.

• Specifications:

  Western blot: 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

• UniProt:

  Q9BT81

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  An E. coli-derived human protein (amino acids K57-D343) was used as the immunogen for the SOX7 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB, Direct ELISA

• Purity:

  Affinity purified

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2% Trehalose

• Reconstitution:

  After reconstitution, the SOX7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This SOX7 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the SOX7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the SOX7 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human 1) COLO-320, 2) PC-3 and 3) A431 cell lysate with SOX7 antibody. Predicted molecular weight: 42/49 kDa (isoforms 1/2) .