Products for Research Use Only
RegisterLogin

HDAC2 Antibody

CAT: 0800-RQ6487Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-RQ6487Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4) . This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al. (1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q92769
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E. coli-derived human protein (amino acids E387-P488) was used as the immunogen for the HDAC2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the HDAC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This HDAC2 antibody is available for research use only.
Storage Conditions
After reconstitution, the HDAC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the HDAC2 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
IHC staining of FFPE human ovarian cancer tissue with HDAC2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Related Products

CatalogName
F43191-0.4MLHDAC4 Antibody
RQ5816HDAC5 Antibody
R30679HDAC3 Antibody
F41123-0.08MLHDAC1 Antibody
V4274SAF-100UGHDAC7 Antibody
F41123-0.4MLHDAC1 Antibody
V9524SAF-100UGHDAC6 Antibody
F43191-0.08MLHDAC4 Antibody
V4274-100UGHDAC7 Antibody
F41165-0.08MLHDAC6 Antibody

Alternative Products

CatalogName
70R-34167HDAC2 antibody
GWB-FA2335HDAC2, Antibody
sc-56685HDAC2 (HDAC2-62)

Popular Products