Cfh Antibody / Complement factor H

Cfh Antibody / Complement factor H

• Description: Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• CAS Number: 9007-83-4
• UniProt: P06909
• Host: Rabbit
• Immunogen: Recombinant mouse protein (amino acids N136-T447) was used as the immunogen for the Cfh antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IHC-P, FACS
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the Cfh antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This Cfh antibody is available for research use only.