Products for Research Use Only

CD22 Antibody

CAT: 0800-RQ5551Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5551Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking. It is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions. The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor. And CD22 is located within the band region q13.1 of chromosome 19.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P20273
Host
Mouse
Reactivity
Human
Immunogen
Amino acids LAILILAICGLKLQRRWKRTQSQQGLQEN were used as the immunogen for the CD22 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
5E7.
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CD22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD22 antibody is available for research use only.
Storage Conditions
After reconstitution, the CD22 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD22 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Raji cell lysate with CD22 antibody. Expected molecular weight: 76-150 kDa depending on glycosylation level.
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