C4A Antibody / Complement C4A

• Description:

  This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. [RefSeq]

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  P0C0L4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human C4A / Complement C4A was used as the immunogen for the C4A antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  AFHB-3

• Type:

  Recombinant

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the C4A antibody at -20oC.

• Limitations:

  This C4A antibody is available for research use only.

• Storage Conditions:

  Store the C4A antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the C4A antibody should be determined by the researcher.

• CAS Number:

  9000-83-3

• Image Legend:

  Western blot testing of human HepG2 cell lysate with C4A antibody. Predicted molecular weight: 193-203 kDa (C4A) and 93-98 kDa (C4A alpha chain) .