Complement C3 Antibody

• Description:

  Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [RefSeq]

• Specifications:

  Western blot: 1:500-1:2000

• UniProt:

  P01024

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide specific to human Complement C3 was used as the immunogen for the Complement C3 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  AEIC-3

• Applications:

  WB

• Purity:

  Affinity purified

• Format:

  Purified

• Limitations:

  This Complement C3 antibody is available for research use only.

• Storage Conditions:

  Store the Complement C3 antibody at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the Complement C3 antibody should be determined by the researcher.

• Image Legend:

  Western blot testing of human MCF7 cell lysate with C3 antibody. Expected molecular weight: ~185 kDa (alpha + beta chain), ~110 kDa (alpha chain) .