HER2 Antibody / ErbB2

HER2 Antibody / ErbB2

• Description :

  The ERBB2 gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. [RefSeq]

• Specifications :

  Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence/Immunocytochemistry: 1:50-1:200

• UniProt :

  P04626

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A synthetic peptide specific to human HER2 / ErbB2 was used as the immunogen for the HER2 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG

• Clone :

  BCI-5

• Type :

  Recombinant

• Applications :

  IHC-P, IF/ICC, WB

• Purity :

  Affinity purified

• Format :

  Purified

• Buffer :

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution :

  Store the HER2 antibody at -20oC.

• Limitations :

  This HER2 antibody is available for research use only.

• Storage Conditions :

  Store the HER2 antibody at -20°C.

• Formulation :

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes :

  Optimal dilution of the HER2 antibody should be determined by the researcher.

• CAS Number :

  9000-83-3

• Image Legend :

  IF/ICC staining of human SK-BR-3 cells with HER2 antibody (green) and DAPI nuclear stain (blue) .