MBD3 Antibody

CAT: 0800-RQ4821Size: 100 µLDry Ice: NoHazardous: No
CAT#:0800-RQ4821Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD) . The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95983
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AFEE-13
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the MBD3 antibody at -20oC.
Limitations
This MBD3 antibody is available for research use only.
Storage Conditions
Store the MBD3 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the MBD3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 293T cell lysate with MBD3 antibody. Predicted molecular weight ~33 kDa.

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