Products for Research Use Only

Epac1 Antibody / RAPGEF3

CAT: 0800-RQ4808Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4808Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade.
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
O95398
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Epac1 / RAPGEF3 was used as the immunogen for the Epac1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AEOG-18
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Epac1 antibody at -20oC.
Limitations
This Epac1 antibody is available for research use only.
Storage Conditions
Store the Epac1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Epac1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HeLa cell lysate with Epac1 antibody. Predicted molecular weight ~104 kDa.

UniProtKB · O95398

Rap guanine nucleotide exchange factor 3

RPGF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RAPGEF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K2G5, E7EQC8, O95634, Q8WVN0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Angiogenesis

Ligand

cAMPcAMP-bindingNucleotide-binding

Molecular function

Guanine-nucleotide releasing factor

Cellular component

Membrane

PTM

Phosphoprotein