Exportin 1 Recombinant Antibody / XPO1 / CRM1

Exportin 1 Recombinant Antibody / XPO1 / CRM1

• Description: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
• CAS Number: 9000-83-3
• UniProt: O14980
• Host: Rabbit
• Immunogen: A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.
• Clonality: Monoclonal
• Isotype: IgG
• Type: Recombinant
• Applications: WB
• Format: Purified
• Buffer: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
• Reconstitution: Store the CRM1 antibody at -20oC.
• Limitations: This CRM1 antibody is available for research use only.