Exportin 4 Antibody

• Description:

  Importins and exportins are transport receptors carrying cargo molecules into and out of the nucleus. Exportin 4 is a member of the Importin B superfamily of RanGTP-binding proteins. Its homology to other family members is restricted to its N-terminal RanGTP-binding motif. Exportin 4 is a nuclear export receptor for eIF-5A, a protein involved in the cellular stress response, functioning as a regulator of p53-mediated and TNF-alpha-mediated apoptosis.

• Specifications:

  Western blot: 1-3 µg/mL

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A recombinant protein fragment from the C-terminal portion of Exportin 4 was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Purity:

  Protein A affinity chromatography

• Format:

  Purified

• Buffer:

  1X PBS, pH 7.4

• Reconstitution:

  Aliquot the Exportin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Exportin 4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Exportin 4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

• Applications Notes:

  Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human samples with Exportin 4 antibody at 1ug/ml.