Products for Research Use Only

LRIG1 Antibody

CAT: 0800-RQ4668Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4668Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene. It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family, MET and RET. This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
Q96JA1
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids AKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYI were used as the immunogen for the LRIG1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the LRIG1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LRIG1 antibody is available for research use only.
Storage Conditions
After reconstitution, the LRIG1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LRIG1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Caco-2 lysate with LRIG1 antibody at 0.5ug/ml. Expected molecular weight: 119-145 kDa depending on glycosylation level. Soluble fragments of 90-105 kDa and 60-70 kDa may also be observed.

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