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DKK1 Antibody

CAT: 0800-RQ4543Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ4543Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O94907
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids T32-H266 from the human protein were used as the immunogen for the DKK1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the DKK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Storage Conditions
After reconstitution, the DKK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the DKK1 antibody should be determined by the researcher.
Image Legend
Western blot testing of recombinant human protein with DKK1 antibody. Predicted molecular weight: 26-40 kDa depending on glycosylation level.
Product Datasheet
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